National Dysautonomia Research Foundation
Support, Education, Research 


Neuroblastoma: known as a sarcoma consisting of malignant neuroblasts, which typically arise in the autonomic nervous system, or in the adrenal medulla. It is considered a type of neuroepithelial tumor and affects mostly infants and children up to the age of ten.

Eighty five percent of cases occur prior to age six, and arises from immature undifferentiated nueroblasts of neural crest origin. Two-thirds of neuroblastomas occur in an adrenal gland, but may also appear where there is sympathetic nerves, such as the chest, pelvis, abdomen, and neck.

Clinical Presentation: may include fever, weight loss, weakness, abdominal discomfort, anorexia, anemia, bone pain, proptosis, pallor, periorbital ecchymoses, easy bruising, neurological manifestations, and metastic subcutaneous nodules, and possible hypertension.


Visit the NDRF Reference Page

View the NDRF Patient Handbook to learn more about the ANS and Dysautonomia


Research and News
Learn About Recent Research on the ANS


Join Our Community
Visit the NDRF Community page to join in discussion and chat.


 Help NDRF's Mission
Support NDRF in our efforts to educate, support and fund research



Search NDRF or the Web: 

The Web NDRF

The National Dysautonomia Research Foundation (NDRF) has established this site to help inform afflicted patients, physicians and the general public on the various forms of Dysautonomia. It is our desire to give timely, as well as, accurate information, however NDRF will not be responsible for the misinterpretation of the information provided.  Questions or problems regarding this web site should be directed to .

Medical questions and information, should be reviewed with your physician. 

Copyright © 1999 NDRF. All rights reserved.
Last modified: Monday January 28, 2008.